HSP90 INHIBITION DECREASES MITOCHONDRIAL PROTEIN TURNOVER.

Hsp90 inhibition decreases mitochondrial protein turnover.

Cells treated with hsp90 inhibitors exhibit pleiotropic changes, including an expansion of the mitochondrial compartment, accompanied by mitochondrial fragmentation and condensed Pillows mitochondrial morphology, with ultimate compromise of mitochondrial integrity and apoptosis.We identified several mitochondrial oxidative phosphorylation complex s

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Numerical simulation of single bubble boiling behavior

The phenomena of a single bubble boiling process are studied with numerical modeling.The mass, momentum, energy and level set equations are solved using COMSOL multi-physics software.The bubble boiling Nets dynamics, the transient pressure field, velocity field and temperature field in time are analyzed, and reasonable results are Signs obtained.Th

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